Sterol Composition of Normal Human Bile

Autor: Beverley E. Phillipson, Don S. Lin, William E. Connor
Rok vydání: 1984
Předmět:
Zdroj: Gastroenterology. 86:611-617
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(84)80107-9
Popis: To examine the sterol composition of normal human bile and the effects of dietary components from certain shellfish upon bile composition, we fed 7 subjects diets rich in shellfish for 2 wk following a typical American diet. The total cholesterol, bile acid, and phospholipid, and the individual sterols and bile acids of the bile samples during each dietary period were measured. In the bile of 7 subjects consuming the typical American diet, nine different neutral sterols, in addition to cholesterol, were identified. Similar patterns of these sterols have been found in human gallstones and in plasma after shellfish feeding. The five shellfish sterols (22-dehydrocholesterol, 24-methylene cholesterol, brassicasterol, isof ucosterol, and a C-26 sterol) increased from 0.3% to a total of 5.2% (p
Databáze: OpenAIRE