Derivatives of (4R)-1,3-thiazolidine-4-carboxylic acid labeled with technetium-99m
| Autor: | Jan Světlík, A. Bumbálová, J. Sivý, Viktor Kettmann, Emil Havránek |
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| Rok vydání: | 1997 |
| Předmět: |
chemistry.chemical_classification
Biodistribution Chromatography Chemistry Health Toxicology and Mutagenesis Carboxylic acid Thiazolidine Public Health Environmental and Occupational Health Pollution Thin-layer chromatography Analytical Chemistry Gel permeation chromatography Electrophoresis chemistry.chemical_compound Nuclear Energy and Engineering Molecular size Radiology Nuclear Medicine and imaging Technetium-99m Spectroscopy |
| Zdroj: | Journal of Radioanalytical and Nuclear Chemistry. 224:163-166 |
| ISSN: | 1588-2780 0236-5731 |
| DOI: | 10.1007/bf02034632 |
| Popis: | The preparation of99mTc-complexes with nine derivatives of (4R)-1,3-thiazolidine-4-carboxylic acid over a broad pH range is described. The labeling efficiency of all compounds was checked by paper- and thin layer chromatography. Paper electrophoresis and gel chromatography indicated the presence of two types of99mTc-complexes differing in charge and molecular size. Preliminary results of the biodistribution of anionic complexes in mice are given. The structure of both types of the Tc-complexes is also discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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