Recurrent Giant-Cell Tumor Presenting as a Soft-Tissue Mass. A Report of Four Cases*

Autor: Susan V. Kattapuram, Francis Young-In Lee, Eric J. Hazan, Suzanne B. Keel, Mark L. Montgomery, Henry J. Mankin
Rok vydání: 1999
Předmět:
Zdroj: The Journal of Bone & Joint Surgery. 81:703-7
ISSN: 0021-9355
DOI: 10.2106/00004623-199905000-00012
Popis: Giant-cell tumor of bone is a benign, locally invasive tumor that has been associated with a rate of local recurrence of 27 percent (forty-one of 151) after intralesional excision and 8 percent (ten of 122) after marginal excision1. The high rate of local recurrence and the occasional development of pulmonary metastasis are manifestations of the locally invasive nature of the tumor4-6,8,9,11,12. A peripheral rim of ossification has been described as an almost pathognomonic sign of a soft-tissue recurrence2,3,11. However, a soft-tissue recurrence can be difficult to detect, especially when the recurrent lesion is asymptomatic and is not associated with the characteristic ossification. We report on four patients who had an isolated soft-tissue recurrence of a giant-cell tumor of bone. Although a radiodense peripheral rim of ossification is thought to be pathognomonic of a soft-tissue recurrence of giant-cell tumor, this finding was not apparent on the plain radiographs of any of these patients. In each case, a soft-tissue mass was palpable on physical examination and magnetic resonance imaging scans revealed a soft-tissue mass with a heterogeneous signal pattern. The purpose of this report is to emphasize that a soft-tissue recurrence may not be recognized if a thorough physical examination is not performed and magnetic resonance imaging studies are not carried out. CASE 1. A forty-two-year-old woman was seen by us because of a rapidly enlarging soft-tissue mass in the posteromedial aspect of the proximal part of the right calf. Twenty-six months previously, the patient had been managed with curettage and bone-grafting because of a giant-cell tumor of the proximal aspect of the right tibia. Six months after the initial treatment, the patient had a recurrence of the giant-cell tumor and was …
Databáze: OpenAIRE