Thyroid disorders in antenatal women in a rural hospital in central India
Autor: | SN Mahajan, C. Hariharan, Deepti S. Shrivastava, Kalyani S. Mahajan |
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Rok vydání: | 2016 |
Předmět: |
Gynecology
endocrine system medicine.medical_specialty Pregnancy endocrine system diseases Anemia business.industry Obstetrics Thyroid Intrauterine growth restriction medicine.disease Miscarriage medicine.anatomical_structure medicine Euthyroid business hormones hormone substitutes and hormone antagonists Hormone Subclinical infection |
Zdroj: | International Journal of Reproduction, Contraception, Obstetrics and Gynecology. :62-67 |
ISSN: | 2320-1770 |
Popis: | Background: Thyroid disorders are one of the most common endocrine disorders in pregnancy. Thyroid disorders are known to be associated with abnormal maternal and fetal outcomes and are often overlooked in pregnant women because of nonspecific symptoms and hypermetabolic state of pregnancy. Methods: 514 women between 12 to 18 weeks of pregnancy from October 2013 to September 2015were recruited in the study. Serum thyroid-stimulating hormone (TSH) testing was done. Free T4 and free T3 were tested in subjects with a deranged TSH value. Subjects were followed up till delivery, and maternal and fetal complications arising out of thyroid dysfunction were studied. Results: The occurrence of subclinical hypothyroidism was 9.54%, overt hypothyroidism was 2.34% and hyperthyroidism was 0.58%. When compared to subjects with euthyroidism, anemia and preterm delivery were the most significant maternal complications in subjects with hypothyroidism (p=0.0001 and 0.0001, respectively) whereas miscarriage, IUD/stillbirth, LBW and intrauterine growth restriction were significant fetal complications observed in subjects with hypothyroidism, with p |
Databáze: | OpenAIRE |
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