The study of Lewis acid effect on asymmetric Diels-Alder reactions of new 2-sulfinylbutadienes derived from (1R, 2S, 3R)-3-mercaptocamphan-2-ol

Autor:	Teng-Kuei Yang, Han-Yang Chu, Dong-Sheng Lee, Yao-Zhong Jiang, Ta-Shue Chou
Rok vydání:	1996
Předmět:	Chemistry Organic Chemistry Drug Discovery Diels alder Organic chemistry Lewis acids and bases Selectivity Biochemistry
Zdroj:	Tetrahedron Letters. 37:4537-4540
ISSN:	0040-4039
DOI:	10.1016/0040-4039(96)00897-0
Popis:	The Diels-Alder reactions of N-phenylmaleimide and new chiral 2-sulfinylbutadienes, which were prepared from MerCO[(1R, 2S, 3R)-3-mercaptocamphan-2-ol], produced cycloadducts up to 99% d.e. in the presence of LiClO4 at ambient temperature. On the other hand, we found the facial selectivity of the cycloaddtion changed greatly among various Lewis acids.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ff3252d457aa3f3c455ad9d13d7a4231 https://doi.org/10.1016/0040-4039(96)00897-0 Zobrazit plný text záznamu Full Text from ScienceDirect