| Autor: |
N G Plekhova, N M Kondrashova, S E Kislova |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Bulletin "Biomedicine and sociology". :23-29 |
| ISSN: |
2618-8783 |
| DOI: |
10.26787/nydha-2618-8783-2021-6-1-23-29 |
| Popis: |
The progression of the inflammatory process and the outcome in community-acquired pneumonia (CAP) depend on the functional activity of innate immune cells - neutrophils and macrophages. Purpose: to establish the relationship between the morphofunctional state of neutrophils and macrophages of induced sputum (inflammation focus) and the severity of community-acquired pneumonia (CAP). Materials and methods: cells were removed from the induced sputum (IS) of healthy individuals and patients with CAP. In the «in vitro» model, upon contact with S. aureus the phagocytic index (PI), number (PN), and index of phagocytosis completion (ICP) were determined. A spectrophotometric method was used to assess the enzymatic activity of cells. Results. The dependence of phagocytosis indices on the severity of CAP was established (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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