Effect of Vitamin E on the Urea Cycle Enzymes, Ornithine-keto Acid Transaminase, and Isocitric Dehydrogenase in Rat Liver
| Autor: | Koichi Shimbayashi, Shigemi Shoya |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Vitamin
medicine.medical_specialty Vitamin E medicine.medical_treatment Ornithine transcarbamylase Ornithine General Biochemistry Genetics and Molecular Biology Transaminase chemistry.chemical_compound Endocrinology Blood serum chemistry Biochemistry Ornithine Carbamoyltransferase Internal medicine Urea medicine General Agricultural and Biological Sciences |
| Zdroj: | Agricultural and Biological Chemistry. 35:983-988 |
| ISSN: | 0002-1369 |
| DOI: | 10.1080/00021369.1971.10860037 |
| Popis: | Albino female rats were fed for 4 to 6 months on either a vitamin E-supplemented or on a vitamin E-unsupplemented diet.Of the urea cycle enzyme activities, carbamyl phosphate synthetase and ornithine transcarbamylase were significantly higher in the vitamin E-supplemented group than in the vitamin E-unsupplemented one. Reversely, the activity of ornithine-keto acid transaminase was lower in the former group.Urea level in the serum and liver was lower in the vitamin E-supplemented group, but urea excretion was accelerated in this group.Activity of isocitric dehydrogenase was significantly higher in the vitamin E-supplemented group. From these results, it is suggested that vitamin E is efficient for the de-toxication of ammonia in the animal body. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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