Interférence sur le dosage de la troponine Ic sur Beckman Coulter DxC600i/880i® : à propos d’un cas d’anticorps hétérophiles
| Autor: | E. Chazalet, Q. Blanc, J. Bronner, J. Sartre, T. Le Bricon, K. Barrial, F. Courtier |
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| Rok vydání: | 2010 |
| Předmět: |
High concentration
medicine.medical_specialty Pathology biology Elevated level Troponin T business.industry Biochemistry (medical) Clinical Biochemistry Troponin Gastroenterology chemistry.chemical_compound Myoglobin chemistry Intensive care Internal medicine Troponin I biology.protein Medicine Ischaemic heart disease business |
| Zdroj: | Immuno-analyse & Biologie Spécialisée. 25:272-275 |
| ISSN: | 0923-2532 |
| DOI: | 10.1016/j.immbio.2010.09.005 |
| Popis: | Summary A 43-year-old man admitted in intensive care of Valence hospital was found with a plasma (lithium-heparin BD Vacutainer®) level of cardiac troponin Ic at 16.76 ng/mL (Beckman Coulter, DxC600i/880i®, level of acute myocardial infarction = 0.5 mg/mL). To face the discord clinical picture and biological results: elevated level of troponin I, normal myoglobin and CK and absence of symptoms in favor of an ischaemic heart disease, a new blood sample was drawn on the same day (troponin Ic: 18.06 ng/mL). Further positive results were obtained on the next days (up to 37.58 ng/mL) without clinical symptom. Following the negative result of troponin T sent to another laboratory, blood specimens were adressed for expertise to Beckman Coulter. Results confirmed the presence of heterophilic antibodies at high concentration interfering with the troponin Ic. |
| Databáze: | OpenAIRE |
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