Occurrence of CNS demyelinating disease in patients with myasthenia gravis
| Autor: | B. G. Weinshenker, A. Jacob, I. Kister, J. Herbert, M. L. Swerdlow, R. Bergamaschi, G. Piccolo, J. Oger, K. Ikeda, Y. Araki, Y. Iwasaki, I . Kister, J . Herbert, M .L. Swerdlow, R . Bergamaschi, G . Piccolo, J . Oger, M. Gotkine, O. Abramsky |
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| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Anti-nuclear antibody business.industry Incidence (epidemiology) medicine.medical_treatment Multiple sclerosis Central nervous system Myelitis Retrospective cohort study medicine.disease Gastroenterology Myasthenia gravis Thymectomy medicine.anatomical_structure Internal medicine Immunology Medicine Neurology (clinical) business |
| Zdroj: | Neurology. 68:1326-1327 |
| ISSN: | 1526-632X 0028-3878 |
| DOI: | 10.1212/01.wnl.0000262954.51568.25 |
| Popis: | An increased incidence of multiple sclerosis (MS) has been reported in patients with myasthenia gravis (MG). We reviewed records of 214 patients with MG. CNS demyelinating disease (CNSDD) occurred in five patients (2.3%). CNSDD always occurred after the diagnosis of MG. Myelitis (including recurrent myelitis) was the most common CNS manifestation. All patients had antinuclear antibodies. CNSDD occurs more frequently in patients with MG and may be related to immune-modulating treatments including thymectomy. |
| Databáze: | OpenAIRE |
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