Decreased susceptibility to imipenem among penicillin-resistant Streptococcus pneumoniae [published erratum appears in J Antimicrob Chemother 1997 Sep;40(3):462]
| Autor: | J M Keith, Joseph M. Campos, J A Donkersloot, Andreas Pikis, S Akram, W J Rodriguez |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Pharmacology
Microbiology (medical) Imipenem Carbapenem Cefotaxime biochemical phenomena metabolism and nutrition Biology bacterial infections and mycoses medicine.disease_cause medicine.disease Meropenem Virology Microbiology Penicillin Pneumococcal infections Infectious Diseases Streptococcus pneumoniae polycyclic compounds medicine Vancomycin Pharmacology (medical) medicine.drug |
| Zdroj: | Journal of Antimicrobial Chemotherapy. 40:105-108 |
| ISSN: | 1460-2091 |
| DOI: | 10.1093/jac/40.1.105 |
| Popis: | We assessed the antimicrobial susceptibilities of 59 penicillin-intermediate or penicillin-resistant pneumococci. All strains were susceptible to vancomycin and rifampicin. The frequency of strains with decreased susceptibility to cefotaxime, chloramphenicol, imipenem and meropenem was 15, 31, 47 and 49% respectively. The high percentage of penicillin-intermediate or penicillin-resistant Streptococcus pneumoniae with decreased susceptibility to third-generation cephalosporins, chloramphenicol and carbapenems limits the therapeutic options for the treatment of invasive pneumococcal infections and particularly of meningitis. |
| Databáze: | OpenAIRE |
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