Monocyte count to high-density lipoprotein cholesterol ratio and mean platelet volume may be related to the severity of carotid artery stenosis

Autor: M S Kuyumcu, V A Ayyildiz, S Ulusan
Rok vydání: 2022
Předmět:
Zdroj: European Journal of Preventive Cardiology. 29
ISSN: 2047-4881
2047-4873
Popis: Funding Acknowledgements Type of funding sources: None. Objective The pathophysiology of carotid artery stenosis (CAD) is not fully understood. Research has shown that mean platelet volume (MPV) is a potential marker for platelet activation and a key factor in the pathophysiology of atherosclerosis. Recently, the ratio of monocyte count to HDL (MHR) has been identified as a predictor of cardiovascular events in patients. In the light of these findings, the goal of this study was to evaluate the potential association of MPV and MHR with the severity of CAD. Material-Method The patients were divided into three groups: CAD≥ 60% (40 patients), CAD Results MPV and MHR levels were lower in the control group than CAD Conclusion In our study, a potential relationship between MPV and MHR with carotid artery disease was determined. Our study may make contributions to understanding the pathophysiology of carotid artery atherosclerosis and developing treatments for it.
Databáze: OpenAIRE