Electrospun PLGA fibre sheets incorporating fluorescent nanosensors: self-reporting scaffolds for application in tissue engineering

Autor:	Helen Harrington, Jonathan W. Aylott, Amir M. Ghaemmaghami, Yvonne Reinwald, Lee D.K. Buttery, F.R.A.J. Rose
Rok vydání:	2013
Předmět:	Scaffold Analyte Materials science General Chemical Engineering technology industry and agriculture General Engineering Nanotechnology 3d model Fluorescence Analytical Chemistry PLGA chemistry.chemical_compound chemistry Tissue engineering Nanosensor
Zdroj:	Anal. Methods. 5:68-71
ISSN:	1759-9679 1759-9660
Popis:	Ratiometric analyte responsive nanosensors have been incorporated into electrospun poly(lactic-co-glycolic) acid (PLGA) fibres to create self-reporting scaffolds. It has been demonstrated that the self-reporting scaffolds could be utilised to monitor microenvironment conditions without damaging the fabricated scaffold or the cells being cultured upon the construct. This presents opportunities to fully understand, monitor and optimise the growth of 3D model tissue constructs in vitro.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fef11cf9854b623ff82f740abc779d8b https://doi.org/10.1039/c2ay25771h Zobrazit plný text záznamu