Abstract WP128: Incidence Of Intracranial Hemorrhage And Clinical Outcomes In Fast Versus Slow Progressors As Defined By Aspects
| Autor: | Sindhu Sahito, Farah Fourcand, Arifa Ghori, ChHassan Ali, Zamir Singh, Rudra Joshi, Abdallah Amireh, Nancy E Gadallah, Navid Tabibzadeh, Siddhart Mehta, Jawad F Kirmani |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Stroke. 54 |
| ISSN: | 1524-4628 0039-2499 |
| Popis: | Introduction: Heterogeneity of collateralization in patients with acute ischemic stroke (AIS) is a marker of fast versus slow progression of penumbral consumption and infarct expansion. Our aim was to evaluate the relationship between time-dependent stroke progression and incidence of intracranial hemorrhage (ICH) and acute neurological deficits. Methods: Retrospective chart review of patients presenting with anterior circulation large vessel occlusion (LVO)-associated AIS at our comprehensive stroke center with 24 hours last known normal (LKN) who underwent endovascular thrombectomy (EVT) without intra-arterial thrombolytics or non-thrombolytics were included. We used Alberta Stroke Program Early CT Score (ASPECTS) on initial non-contrast CT to identify slow versus fast progressors. ASPECTS Results: From September 2019 to December 2021, out of 268 subjects who underwent EVT, 48 met inclusion criteria. Mean age was 65.29 (95% CI 61.32, 69.27), and median presenting NIHSS was 16 (95% CI 14.39, 18.40). Mean ASPECTS was 7.71 (95% CI 7.21, 8.20). There was significant difference is hemorrhagic transformation rate between ASPECTS >7 and Conclusion: Our study suggests that ASPECTS score as assessed in different time windows to differentiate fast versus slow progressors is not only a predictor of clinical outcome, but also independently associated with risk of hemorrhagic transformation. Larger, prospective studies are needed to validate our results. |
| Databáze: | OpenAIRE |
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