A novel CSF1R-c-kit dual antagonist eliminates tumor associated macrophage without elevating intratumoral MDSC level

Autor: Cindy Chen, Yu Zhiyong, Pang Wei, Keke Chen, Liu Shifeng, Qingchong Qiu, Wang Ji
Rok vydání: 2019
Předmět:
Zdroj: Annals of Oncology. 30:vi125
ISSN: 0923-7534
DOI: 10.1093/annonc/mdz343.036
Popis: Results After review of the pre-specified IA, the IDMC recommended full analysis and disclosure of the results. With 256 IDFS events reported, administration of T-DM1 significantly improved IDFS compared with trastuzumab (unstratified HR = 0.50; 95% CI: 0.39 to 0.64; p
Databáze: OpenAIRE