Sa1712 Inducible Macrophage Ablation Protects Mice From Non-Alcoholic Steatohepatitis

Autor:	Eagle Sh Chu, Xiang Zhang, Joseph J.Y. Sung, Ruonan Wu, Jun Yu
Rok vydání:	2014
Předmět:	Hepatology business.industry medicine.medical_treatment Gastroenterology Non alcoholic Diagnostic marker medicine.disease Ablation Downregulation and upregulation medicine Cancer research Macrophage Steatohepatitis business
Zdroj:	Gastroenterology. 146:S-957
ISSN:	0016-5085
Popis:	tion of miR-122 underexpression with steatohepatitis. To our knowledge, this is the first report of underexpression of miR-370 in steatohepatitis. This result is mechanistically consistent with a previous study that showed upregulation of miR-122 by miR-370. Our findings suggest that miR-122 and miR-370 in particular may have a role in the progression of NAFLD and could be useful as diagnostic markers to differentiate different stages of NAFLD.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::febaa25ecc0e6047be19c470994a2cce https://doi.org/10.1016/s0016-5085(14)63484-3 Zobrazit plný text záznamu