¿Son útiles la proteína C reactiva y la procalcitonina para el diagnóstico precoz de la infección intraabdominal después de una duodenopancreatectomía por cáncer de páncreas?
| Autor: | Nazaret Quiroga-Veiga, Sergio Estévez-Fernández, Elías Domínguez-Comesaña, Victoria López-Gómez, Rubén Domínguez-Fernández |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Intraabdominal infection biology business.industry medicine.medical_treatment C-reactive protein 030230 surgery medicine.disease Pancreaticoduodenectomy Gastroenterology Procalcitonin 03 medical and health sciences 0302 clinical medicine Internal medicine Pancreatic cancer medicine biology.protein Surgery In patient business |
| Zdroj: | Cirugía y Cirujanos. 87 |
| ISSN: | 0009-7411 |
| DOI: | 10.24875/ciru.19000855 |
| Popis: | Objective To evaluate the relationship between C reactive protein and procalcitonin levels and the appearance of post-operative intraabdominal infection, in patients with pancreaticoduodenectomy due to pancreatic cancer. Method A prospective observational study, including 35 patients, was made. Procalcitonin and C reactive protein were measured before surgery, as well as 24, 48 and 72 h after the surgical procedure. Patients were divided in two groups, with and without intraabdominal infection. Results Six patients (17.1%) presented post-operative intraabdominal infection. Both, procalcitonin and C reactive protein, increased in all patients after surgery, but there were no significant differences between the two groups. However, the ratio between the C reactive protein concentrations on post-operative day 3 and the concentrations on post-operative day 1 was significantly increased in the group of patients with intraabdominal infection. The predictive positive value and the predictive negative value for this ratio were 60% and 95%, respectively, for a cut-off point of 2.3. Conclusions The ratio between C reactive protein value on post-operative day 3 and the value on post-operative day 1 is a good predictor of post-operative intraabdominal infection after pancreaticoduodenectomy. |
| Databáze: | OpenAIRE |
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