TU-C-332-01: A Comparison of Initial Area Under Curve (IAUC) Obtained From DCE-CT and -MR Imaging in Patients with Cervical Cancer

Autor: M. Milosevic, S Kim, M. Haider, E. Maheshwari, Ivan Yeung
Rok vydání: 2008
Předmět:
Zdroj: Medical Physics. 35:2893-2894
ISSN: 0094-2405
DOI: 10.1118/1.2962488
Popis: Purpose: To compare the IAUC60 (initial area under curve taken up to 60 seconds) obtained from DCE‐CT and ‐MR imaging in patients with cervical cancer.Method and Materials: A group of 40 patients with cervical cancer received a DCE‐MRI scan followed by a DCE‐CT scan at the time of staging. A radiologist observer identified and contoured the tumours on CT and MR images. At least one slice was identified as the matching slice in the CT and MR images for each patient. IAUC60 obtained from tumour region was normalized by IAUC60 from muscle region for DCE‐CT and ‐MR data. Correlation study and Bland‐Altman analysis were performed to assess the relationship between the normalized IAUC60 obtained from the two imaging modalities. Regression analysis was also applied to assess the relationship between the normalized IAUC60 and the normalized transfer constant (rK trans) for DCE‐CT data. Results: The regression analysis between the normalized IAUC60 and the normalized transfer constant (rK trans) for DCE‐CT data resulted in a significant strong correlation (R = 0.98, P
Databáze: OpenAIRE