Platelet‐to‐lymphocyte ratio better predicts inflammation than neutrophil‐to‐lymphocyte ratio in end‐stage renal disease patients
| Autor: | Levent Demirtas, Kultigin Turkmen, Adalet Ozcicek, Suleyman Turk, Emin Murat Akbas, H. Zeki Tonbul, Fatih Mehmet Erdur, Fatih Ozcicek, Aysu Ozbicer |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
education.field_of_study business.industry Lymphocyte medicine.medical_treatment fungi Population Interleukin Inflammation Hematology Gastroenterology Peritoneal dialysis End stage renal disease body regions medicine.anatomical_structure Nephrology Internal medicine Immunology medicine Hemodialysis medicine.symptom Neutrophil to lymphocyte ratio business education |
| Zdroj: | Hemodialysis International. 17:391-396 |
| ISSN: | 1542-4758 1492-7535 |
| DOI: | 10.1111/hdi.12040 |
| Popis: | Neutrophil-to-lymphocyte ratio (NLR) was introduced as a potential marker to determine inflammation in end-stage renal disease (ESRD) patients. Recently, platelet-to-lymphocyte ratio (PLR) and NLR were found to positively correlated with inflammatory markers including tumor necrosis factor-α (TNF-α) and interleukin (IL)-6 in cardiac and noncardiac patients. Data regarding PLR and its association with inflammation are lacking in hemodialysis (HD) and peritoneal dialysis (PD) patients. Hence, we aimed to determine the relationship between PLR, NLR, and inflammation in ESRD patients. This was a cross-sectional study involving 62 ESRD patients (29 females, 33 males; mean age, 49.6 ± 14.6 years) receiving PD or HD for ≥6 months in the Dialysis Unit of Necmettin Erbakan University. PLR, NLR, C-reactive protein, TNF-α, IL-6 levels were measured. PLR, NLR, serum high sensitive C-reactive protein, IL-6, and TNF-α levels were significantly higher in PD patients when compared with HD patients. ESRD patients with PLR ≥ 140 had significantly higher NLR, IL-6, and TNF-α levels when compared to patients with PLR |
| Databáze: | OpenAIRE |
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