Investigation of Degradation Properties of Poly(lactide-co-glycolide) Matrix for Anticancer Agent Delivery

Autor: S. M. Ghani, M. S. W. Mohamed, A. F. Yahya, K. Noorsal, Mohamad Rusop, Rihanum Yahaya Subban, Norlida Kamarulzaman, Wong Tin Wui
Rok vydání: 2010
Předmět:
Zdroj: AIP Conference Proceedings.
ISSN: 0094-243X
DOI: 10.1063/1.3377816
Popis: Poly(lactide‐co‐glycolide) (PLA50GA50) is a biodegradable and biocompatible polymer. It offers tremendous potential as a basis for drug delivery, either as drug delivery system alone or in conjugate with a medical device. The PLA50GA50 is the material of choice for relatively shorter‐duration applications, while the homopolymer PLA (poly‐L‐lactide) and PGA (polyglycolide) are preferred for longer term delivery of drugs. This paper discusses the degradation properties of poly(lactide‐co‐glycolide) (PLA50GA50) at inherent viscosity of 0.89 dL/g as preliminary studies for anticancer agent delivery.
Databáze: OpenAIRE