Two-dimensional tritium–proton nuclear Overhauser effects in proteins

Autor:	Phillip G. Williams, John T. Gerig, Thomas M. O’Connell
Rok vydání:	1990
Předmět:	Chymotrypsin biology Proton Chemistry Active site Nuclear Overhauser effect chemistry.chemical_compound Crystallography Nuclear magnetic resonance Tosyl biology.protein Molecular Medicine Tritium Derivative (chemistry)
Zdroj:	J. Chem. Soc., Chem. Commun.. :1502-1503
ISSN:	0022-4936
DOI:	10.1039/c39900001502
Popis:	Two-dimensional 3H {1H} NOE experiments have been used to examine an α-tritiated tosyl derivative of chymotrypsin, demonstrating the feasibility of such experiments with a material of Mr 25 000 and revealing through-space dipolar interaction at the active site of the enzyme.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fe90f04d8bdeaf1b553f2bee3420a7f1 https://doi.org/10.1039/c39900001502 Zobrazit plný text záznamu