Quantitative characteristics of the rapid regeneration of hematopoiesis phenomenon following thymocyte transplantation

Autor:	M. I. Fedotova, Yu. I. Zimin
Rok vydání:	1975
Předmět:	Pathology medicine.medical_specialty Regeneration (biology) Stimulation General Medicine Biology General Biochemistry Genetics and Molecular Biology In vitro Andrology Transplantation Thymocyte Haematopoiesis medicine.anatomical_structure medicine Bone marrow Incubation
Zdroj:	Bulletin of Experimental Biology and Medicine. 80:750-752
ISSN:	1573-8221 0007-4888
Popis:	Quantitative characteristics of the phenomenon of rapid postirradiation regeneration of the bone marrow following transplantation of syngeneic thymocytes were obtained in experiments on (CBA x C57BL)F1 hybrid mice. Within the range 106–108 cells the effect was shown to be independent of the number of transplanted thymocytes. Transplantation in the first 12 h after irradiation was equally effective as regards stimulation of regeneration of the bone marrow. The phenomenon did not appear under the following conditions: a) transplantation of thymocytes 24 h after irradiation; b) irradiation of the recipients in a dose of 600–700 R; c) irradiation of a suspension of thymocytes in vitro in a dose of 10 kR followed by incubation at 37°C for 6–7 h; d) irradiation of the thymocytes in vitro in a dose of 200 kR.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fe56916970d271fd4a2d952406ad8c82 https://doi.org/10.1007/bf00809878 Zobrazit plný text záznamu Full text from SpringerLink