Synthesis of tetrazines from gem-difluoroalkenes under aerobic conditions at room temperature

Autor:	Wen-Li Hu, De-Yong Liu, Xiang-Guo Hu, Zheng Fang, Chu-Yi Yu
Rok vydání:	2017
Předmět:	010405 organic chemistry Chemistry Environmental Chemistry Organic chemistry 010402 general chemistry 01 natural sciences Pollution 0104 chemical sciences Ambient air
Zdroj:	Green Chemistry. 19:1299-1302
ISSN:	1463-9270 1463-9262
Popis:	An efficient and green procedure for the synthesis of tetrazines has been developed based on an old chemistry reported by Carboni in 1958. Both symmetric and asymmetric 3,6-disubstituted 1,2,4,5-tetrazines can be obtained in moderate to high yields from the corresponding gem-difluoroalkenes under aerobic conditions at room temperature. This work represents a rare example that ambient air is utilized as an oxidant for the synthesis of tetrazines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fe48cb92792f4cb5f142784a55701062 https://doi.org/10.1039/c6gc03494b Zobrazit plný text záznamu