MUCIN-LIKE CARCINOMA-ASSOCIATED ANTIGEN (MCA) SERUM LEVELS IN BREAST-CANCER - A CRITICAL-APPRAISAL
| Autor: | G. Micelli, Francesco Schittulli, A. Donadeo, Michele Quaranta, A Muncipinto, Vito Lorusso |
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| Rok vydání: | 1993 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Oncogene Cancer Biology medicine.disease Molecular medicine nervous system diseases Breast cancer Antigen Internal medicine cardiovascular system medicine Cancer research Carcinoma cardiovascular diseases Breast disease circulatory and respiratory physiology Tumor marker |
| Zdroj: | International Journal of Oncology. |
| ISSN: | 1791-2423 1019-6439 |
| DOI: | 10.3892/ijo.2.2.335 |
| Popis: | MCA serum levels were determined in 196 patients with benign breast disease (BD) and in 371 patients with breast cancer. MCA values were abnormal in 30.6% of the patients with BD. In breast cancer patients, significant increases were only found in metastatic disease (89.1%). MCA levels were not correlated with tumor size; on the contrary, the tumor marker showed a strict relation to axillary lymph node involvement. Moreover, the location of metastases and the number of sites involved seem to increase MCA concentrations. The MCA antigen seems to be a promising tool only for monitoring patients with advanced breast cancer. |
| Databáze: | OpenAIRE |
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