The Frequency of Tumor Necrosis Factor-alpha Gene Polymorphism in Patients with Chronic Immune Thrombocytopenia

Autor: Nermin Raafat Abdel-Fattah, Usama El-Safy, Marwa Zakaria Mohamed, nehal tarek elgohary
Rok vydání: 2021
Předmět:
Zdroj: Zagazig University Medical Journal.
ISSN: 2357-0717
DOI: 10.21608/zumj.2021.16776.1504
Popis: Background: The aim of this study was to reveal the frequency of Necrosis Factor _Alpha Gene Polymorphism in evaluation of severity and outcome of chronic immune thrombocytopenia in pediatric department of Zagazig University hospitals. Methods: We conduct a retrospective case control on 40 children diagnosed with chronic ITP and 40 age and sex healthy matched subjects as a control recruited from outpatient hematology clinic Faculty of Medicine, Zagazig University. Results: We found a highly significant difference between ITP group and control group as regarding TNF-α alleles where A allele was expressed in 43.7% of cases versus 17.5% 0f control, P value
Databáze: OpenAIRE