Autor:	Károly Mazák, Béla Noszál, András Nemes
Rok vydání:	1999
Předmět:	Pharmacology Aqueous solution Chemistry Organic Chemistry Vincamine Alkalinity Pharmaceutical Science Protonation Stereoisomerism Vinpocetine medicine Molecular Medicine Organic chemistry Pharmacology (medical) Titration Solvent effects Biotechnology medicine.drug
Zdroj:	Pharmaceutical Research. 16:1757-1763
ISSN:	0724-8741
DOI:	10.1023/a:1018966318167
Popis:	Purpose. The determination of protonation macroconslants of twelve compounds in the vincamine drug family and the determination of protonation microconstants of cis- and trans-apovincaminic acid in media of various solvent composition to characterise their site-specific basicity and to estimate the concentration of the membrane-penetrating and receptor-binding forms.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fe01686b7919e50768cba23d0716ac89 https://doi.org/10.1023/a:1018966318167 Zobrazit plný text záznamu Full text from SpringerLink