Ibudilast (Ketas) in Meniere's Disease

Autor: Keisuke Mizuta, Takahiko Kumada, Hikari Koizumi, Tomoo Suzuki, Hideo Miyata, Mitsuhiro Aoki, Shigeo Sawai, Shinji Sakuma, Yatsuji Ito
Rok vydání: 1994
Předmět:
Zdroj: Equilibrium Research. 53:429-436
ISSN: 1882-577X
0385-5716
DOI: 10.3757/jser.53.429
Popis: To assess the efficacy of Ibudilast in Meniere's desease, we randomly selected 15 patients with this desease seven males and eight females aged 30 - 73 years.We administered three capsules of Ketas® every day to these patients and investigated the following : 1) effect of treatment on vertigo, 2) effect of treatment on damage to the inner ear, 3) effect of treatment on recurrent attacks of vertigo. The effect of treatment on recurrent attacks of vertigo was evaluated by comparing the number of attacks a months after the start of treatment with the number before treatment.Treatment reduced recurrent attacks of vertigo in 11 patients (73%).No side effects were reported in this study.We conclude that Ketas® may be an effective drug for Meniere's disease.
Databáze: OpenAIRE