GASTROPROTECTIVE PROPERTIES OF METAPROT AND DIOSMIN

Autor: Nadezhda Olegovna Kryukova, Petr D. Shabanov, Vasily Egorovich Novikov, Alexandr Sergeevich Novikov
Rok vydání: 2012
Předmět:
Zdroj: Reviews on Clinical Pharmacology and Drug Therapy. 10:35-38
ISSN: 2542-1875
1683-4100
DOI: 10.17816/rcf10135-38
Popis: Intragastric administration of acetylsalicylic acid induces development of NSAID-gastropathy in animals. The number of ulcers and the total area of erosive injury in the mucous membrane are studied. Antioxidants/antihypoxants metaprot in a daily dose of 50 mg/kg and diosmin in a daily dose of 100 mg/kg render gastroprotective action. The gastroprotective properties of both drugs are seems to connected with their reparative and antioxidative activity.
Databáze: OpenAIRE