Bio-screening of a few green seaweeds from India for their cytotoxic and antioxidant potential
| Autor: | Anil Chatterji, Sabu Appukuttan Sudha, Rashmi C Vinayak |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Nutrition and Dietetics
Antioxidant biology DPPH medicine.medical_treatment In vitro toxicology Brine shrimp Antioxidant potential biology.organism_classification Caulerpa racemosa chemistry.chemical_compound chemistry Botany medicine Cytotoxic T cell Bioassay Food science Agronomy and Crop Science Food Science Biotechnology |
| Zdroj: | Journal of the Science of Food and Agriculture. 91:2471-2476 |
| ISSN: | 0022-5142 |
| DOI: | 10.1002/jsfa.4490 |
| Popis: | BACKGROUND: It has been evidenced in several epidemiological studies that seaweeds when consumed as diet protect against several chronic oxidative stress-related diseases. Seaweeds, raw, cooked, or dried, are used as food in many cultures, although not very popularly in India. Globally, several studies have indicated that seaweeds are a rich source of phenolic compounds and have antioxidant properties. In the present study, we screened methanolic extracts (MEs) of five species of green seaweeds commonly found in India for their cytotoxic activity by brine shrimp lethality assay and antioxidant properties using various in vitro assays, including 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, reducing power and metal ion chelating assays. RESULTS: A markedly variable, dose-dependent activity was observed in all the seaweed extracts relative to their total phenolic content. Statistical analysis indicated a significantly strong correlation between the DPPH radical scavenging activity and total phenolic content (R2 = 0.88, P 0.05) was noted. None of the seaweed extracts were potently cytotoxic. CONCLUSION: The underlying results endorse seaweeds as a rich, novel source of antioxidant compounds needing systemic exploration. Copyright © 2011 Society of Chemical Industry |
| Databáze: | OpenAIRE |
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