| Popis: |
This study investigated the effects of exercise and dietary iron on iron status in 13 mo old female rats. Forty-seven 13 mo old female Sprague-Dawley rats (mean weight, 285±3 g) were randomly assigned to one of four treatment groups: 40ppm iron, exercise (40E), 40ppm iron, no exercise (40NE), 9ppm iron, exercise (9E) or 9ppm, no exercise (9NE). The exercise protocol involved swimming the animals in the exercise groups for 6 wk, starting from 10 min/d until the rats were swimming for 60 min/d, 5 d/wk. Results indicated no significant differences in food intake, body weight, or hematocrit among groups. Serum total iron binding capacity was not significantly different between the exercise groups. Serum iron in the 40NE was significantly higher than that in the 40E (340±16 μ g versus 285 SEM 16 μ g). No significant difference in serum iron was observed in 9E and 9NE groups. Iron concentrations in the liver and spleen were significantly lower in the 9E (169±6 μ g, 2.4±0.1 mg) than in the 9NE (182±6 μ g, 2.8±0.1 mg), 40E (197±6 μ g, 2.7±0.1 mg) or 40NE (242±6 μ g, 3.9±0.1 mg). Iron concentration in the gastrocnemius was significantly higher in the 40NE (33.5±0.9 μ g) than in the 40E (28.5±0.9 μ g), 9E (24.1±0.9 μ g), or 9NE (23.1±0.9 μ g). The results indicate lower iron stores in the liver, spleen and gastrocnemius of exercising rats and suggest that there may be an iron cost associated with physical training of 13 mo old female rats. |
