A Review on Effects of High Fructose Diet on Oxidative Stress and Metabolic Syndrome in Male Wistar Rats

Autor: Harshal Patodkar, Mahalaxmi Mohan
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Pharmaceutical Sciences Review and Research. :46-50
ISSN: 0976-044X
Popis: Consumption of high fructose is potently related to the development of hypertension and metabolic syndrome. This theory is supported by observational and experimental studies in animals and humans. Rising consumption of fructose has been matched with growing rates of hypertension and hyperglycemia. A high fructose diet has been found to activate vasoconstrictors and inactivate vasodilators. Salt reabsorption a reason for the increase in blood pressure is also shown by excess consumption of fructose. The fructose-taking diet in the rat causes modifications in the triglyceride concentrations in serum, liver TBARS, liver catalase, and SOD activity. In conclusion, the fructose diet caused significant liver damage and a reduction in insulin sensitivity.
Databáze: OpenAIRE