MRI for the Diagnosis and Follow-Up of Myocarditis

Autor: Bruno Polletta, M. Giulia Gagliardi, Paolo Di Renzi
Rok vydání: 1999
Předmět:
Zdroj: Circulation. 99
ISSN: 1524-4539
0009-7322
DOI: 10.1161/circ.99.3.457/a
Popis: To the Editor: We read with interest the elegant study by Friedrich and associates1 about the usefulness of MRI in the evaluation of myocardial changes in acute myocarditis. The authors evaluated the variation in T1-weighted sequences with gadolinium enhancement over time in 19 patients with clinically suspected myocarditis. In 7 patients, an endomyocardial biopsy (EMB) was also performed, and the morphological pattern was compared with the MRI acquirements to assess correlation between the 2 diagnostic tools. They conclude that contrast-enhanced, T1-weighted sequences performed during the first 2 weeks after the onset of symptoms elucidate the evolution of the inflammatory process from a focal to a diffuse myocardial disease. They also state that T2-weighted sequences yield a poorer-quality image, with signal intensity being not statistically different from controls. In contrast, it has been our experience2 that MRI T2-weighted sequences are able to discern patients with or without myocarditis. We are currently performing a study on 75 consecutive pediatric patients with symptoms …
Databáze: OpenAIRE