Subclinical Peripheral Nerve Affection in Hypothyroidism
| Autor: | Abeer K. El-Zohiery, Mai Abdelazeem, Mohamed Ragaai, Mona Elhussieny |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Pediatrics medicine.diagnostic_test business.industry 030209 endocrinology & metabolism Neurological examination Physical examination medicine.disease Asymptomatic 03 medical and health sciences 0302 clinical medicine Endocrinology medicine.anatomical_structure Internal medicine Nerve conduction study medicine Entrapment Neuropathy Carpal tunnel 030212 general & internal medicine medicine.symptom business Polyneuropathy Subclinical infection |
| Zdroj: | The Egyptian Journal of Hospital Medicine. 67:553-563 |
| ISSN: | 2090-7125 1687-2002 |
| DOI: | 10.12816/0037806 |
| Popis: | Background: Hypothyroidism is most common endocrinal disorder. The existence of hypothyroid neuropathy is a point of debate and its pathogenesis is incompletely understood. Objective: To detect subclinical motor or sensory peripheral nerve affection among hypothyroid patients. Methods: The study was conducted on 30 hypothyroid patients without any neurological symptoms and signs. 10 healthy subjects were included as a control group. All participants were subjected to full medical history taking thorough clinical examination; full general and neurological examination, laboratory & radiological investigations and neurophysiologic nerve conduction study. Results: The study revealed polyneuropathy, mainly sensorimotor, in 86.6% of the patients either axonal demyelination or axonal affection. Median and peroneal nerves were the dominantly affected nerves. High incidence of entrapment neuropathy was encountered among the patients especially carpal tunnel CTS (66.67%).Conclusion: Hypothyroidism is associated with polyneuropathy,mainly of a mixed type (axonal -demyelinating type).Nerve conduction tests should be performed routinely in hypothyroid patients early in the course of the disease, even among asymptomatic patients, to minimize structural damage and disability. |
| Databáze: | OpenAIRE |
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