Frecuencia de los genes de fusión TEL/AML1 y BCR/ABL en pacientes pediátricos con leucemia linfoblástica aguda

Autor:	María Elena Cabrera C, Angélica Melo A, Iván Roa E, Juan Carlos Roa S, Carmen Astete A, Eduardo Páez F, Carmen Gloria Artigas A, Mónica Arriagada M
Rok vydání:	2006
Předmět:	TEL/AML1 Fusion Protein Fusion gene ABL Oncogene Proteins hemic and lymphatic diseases breakpoint cluster region Chromosomal translocation General Medicine Biology neoplasms Fusion protein Virology Molecular biology
Zdroj:	Revista médica de Chile. 134
ISSN:	0034-9887
DOI:	10.4067/s0034-98872006001100003
Popis:	TEL/AML 1 and BCR/ABL fusion gene transcriptswere detected in 13 (23%) and 2 (4%) children, respectively. No differences in survival wereobserved between children with positive or negative transcripts for TEL/AML1 fusion gene. However,those positive for BCR/ABL fusion gene, had a significantly lower survival.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fd855e26bba6b7cf5cd12333847e0cf4 https://doi.org/10.4067/s0034-98872006001100003 Zobrazit plný text záznamu