ADP-induced Platelet Aggregation in Diabetes mellitus
| Autor: | Yasuhiro Oribe, Haruo Uzawa, Nobuhisa Nakamura |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
medicine.medical_specialty
Diabetic neuropathy business.industry Retinal General Medicine Diabetic retinopathy medicine.disease Nerve conduction velocity chemistry.chemical_compound Peripheral neuropathy Endocrinology chemistry Internal medicine Diabetes mellitus medicine Platelet business Retinopathy |
| Zdroj: | Blood & Vessel. 10:523-526 |
| ISSN: | 1884-2372 0386-9717 |
| DOI: | 10.2491/jjsth1970.10.523 |
| Popis: | ADP-induced platelet aggregation at final concentration of 2μM (ADP-Agg.) was performed according to the method by Born using a Bryston aggregometer model 350. The sensitivity of the platelets was expressed in terms of the maximum percentage of light transmittance to that of platelet-poor-plasma within 5 minutes after the addition of ADP. Peripheral neuropathy was evaluated by motor nerve conduction velocity (M. C. V.). Retinopathy was evaluated by usual ophthalmoscopy.The subjects studied were 20 age-matched healthy subjects and 47 diabetic patients. These 47 diabetic patients were divided into following four groups according to their M. C. V. and with or without retinopathy. N (-) indicates the patient whose M. C. V. was not less than the mean M. C. V. of age-matched normal subjects. R (-) indicates the patient whose fundoscopic findings revealed nothing remarkable as to diabetic retinopathy, e. g. microaneurysm, retinal hemorrhage etc. The results of two-sample t test of ADP-Agg. were significant between the groups listed as follows. The figures in parenthesis indicate the number of subjects.P R(-) N(-) (16)P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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