Prenatal Entrainment of Rat Testicular Malate Dehydrogenase Activity Circadian Rhythm
| Autor: | S L Bellivía, N T Vermouth, A R Carpentieri |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
endocrine system
medicine.medical_specialty Fetus Physiology Offspring Biology Malate dehydrogenase Melatonin Endocrinology Physiology (medical) Internal medicine medicine Gestation Circadian rhythm Entrainment (chronobiology) hormones hormone substitutes and hormone antagonists Ecology Evolution Behavior and Systematics Hormone medicine.drug |
| Zdroj: | Biological Rhythm Research. 27:302-313 |
| ISSN: | 1744-4179 0929-1016 |
| DOI: | 10.1076/brhm.27.3.302.12968 |
| Popis: | In mammals the photoperiodic synchronization of circadian system starts before birth. During fetal and neonatal period mothers relay the photoperiodic information to their litter. The maternal pineal melatonin 24 h cycle acts as a synchronizing signal. We have studied the effect of pineal maternal sympathetic denervation and administration of melatonin to mothers denervated during gestation on the prenatal synchronization of testicular malate dehydrogenase (MDH) activity circadian rhythm of the offspring 25 days after birth. When mothers were denervated at the 7th, 10th or 11th day of gestation, pups showed disruption of testicular MDH activity circadian rhythms. In contrast, no disruptive effect was observed when the mothers were denervated on the 12th or 14th day of gestation. When denervated mothers (7th day of gestation) were treated with a daily dose of melatonin from the 11th to the 14th day of gestation, pups showed a MDH activity circadian rhythm. The hormone failed to impose a daily phase when ad... |
| Databáze: | OpenAIRE |
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