New strategy for the synthesis of (+/-) latifine and cherylline dimethyl ether

Autor:	Ramya Soundararajan, A. Sanjeev Kumar, Samir Ghosh, G. N. Mehta, J. Ramanatham
Rok vydání:	2009
Předmět:	chemistry.chemical_compound chemistry Organic Chemistry Magnesium bromide Nitro Dimethyl ether Benzene Medicinal chemistry Cherylline
Zdroj:	Arkivoc. 2009:173-180
ISSN:	1551-7012
DOI:	10.3998/ark.5550190.0010.c15
Popis:	A concise route for the synthesis of (+/-)-latifine and (+/-)-cherylline dimethyl ethers is reported. The key steps involved are the Michael type addition of p-methoxybenzene magnesium bromide to the (E)-1,2-dimethoxy-3-(2-nitrovinyl)benzene, reduction of the nitro intermediate obtained followed by the Pictet-Spengler cyclization and reductive N-methylation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fd6cbfa474c8808f73422d7bbd500d2d https://doi.org/10.3998/ark.5550190.0010.c15 Zobrazit plný text záznamu Plný text ve formátu PDF