Liver enzyme elevation caused by a compression of infiltrative lipoma in a dog
| Autor: | Manabu Kurihara, Ronald Green, Robert J. Bahr |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pathology
medicine.medical_specialty Angiolipoma 040301 veterinary sciences Connective tissue Adipose tissue Liposarcoma 0403 veterinary science 03 medical and health sciences 0302 clinical medicine Biopsy otorhinolaryngologic diseases medicine Fibrolipoma General Veterinary medicine.diagnostic_test business.industry Soft tissue 04 agricultural and veterinary sciences Lipoma medicine.disease body regions stomatognathic diseases medicine.anatomical_structure 030211 gastroenterology & hepatology business |
| Zdroj: | International Journal of Veterinary Science and Medicine. 6:127-129 |
| ISSN: | 2314-4599 |
| DOI: | 10.1016/j.ijvsm.2018.02.005 |
| Popis: | Adipose masses, especially lipoma, are considerably common in veterinary medicine. The current WORLD HEALTH ORGANIZATION (WHO) classification of mesenchymal skin and soft tissue tumors of domestic animals recognizes three benign forms of the adipose tissue, represented by lipoma, infiltrative lipoma and angiolipoma, and one malignant form, represented by liposarcoma [1]. Infiltrative lipoma was first reported in veterinary medicine in 1979 [2]. Infiltrative lipomas differ from malignant adipose tissue mass as in liposarcoma, but they show a more aggressive behavior by invading adjacent structures such as muscle, fasciae, spinal cord, joint capsule and cervical bone [3], [4], [5], [6], [7], [8], [9]. The reported local recurrence rate of infiltrative lipoma is high, ranging from 36 to 50% [10], [11]. On the other hand, lipoma is a benign, soft, encapsulated, moderately discrete neoplasm consisting of differentiated fat cells, which seldom recur after surgery. Fibrolipoma and angiolipoma are uncommon variants of lipoma, being classified and diagnosed histopathologically. Fibrolipoma contains adipose tissue and bundles of collagenous connective tissue. Angiolipoma is composed of mature adipose tissue mixed with variable numbers of blood vessels [12]. The cells of a simple lipoma and infiltrative lipoma are histologically similar. Well-differentiated unilocular fat cells infiltrate the tissues, causing separation of fibers and atrophy [11]. Therefore, Infiltrative lipomas cannot be diagnosed accurately with either a fine-needle aspiration or a Tru-Cut biopsy. Aspiration cytology was performed on 16 infiltrative lipomas, and in each instance the cytologic diagnosis was lipoma, not infiltrative lipoma [10]. In this case, a large infiltrative lipoma invaded the adjacent tissue and compressed the left liver lobe, causing liver enzyme elevation. To the authors’ knowledge, an elevation of liver enzymes is caused by a compression of infiltrative lipoma and pathologic findings of the compressed liver have not been reported. |
| Databáze: | OpenAIRE |
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