SERS detection and analysis of a single DNA oligomer using a single gold nanoparticle dimer

Autor:	Koji Sugano, Katsunari Maruoka, Yoshitada Isono
Rok vydání:	2017
Předmět:	010302 applied physics Materials science Dimer Nanoparticle 010402 general chemistry Photochemistry 01 natural sciences Oligomer 0104 chemical sciences Nucleobase chemistry.chemical_compound symbols.namesake chemistry 0103 physical sciences symbols Self-assembly Raman spectroscopy DNA Plasmon
Zdroj:	2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS).
DOI:	10.1109/transducers.2017.7994087
Popis:	This paper reports surface-enhanced Raman spectroscopy (SERS) analysis of a single DNA oligomer toward SERS-based reliable DNA sequencing using a single gold nanoparticle dimer. Due to the Raman enhancing hotspot with 1-nm nanogap in the single dimer, for the first time, the single oligomer detection and analysis was demonstrated. The dimer identified the several bases and backbone components of the single DNA oligomer. The dynamics of the single oligomer could be analyzed. The oligomer was trapped and stayed at the nanogap hotspot, and fluctuated with rotation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fd59c31043351b1edbcf3aab18338db6 https://doi.org/10.1109/transducers.2017.7994087 Zobrazit plný text záznamu