Two novel SNPs of the type I gonadotropin releasing hormone receptor gene and their associations with superovulation traits in Chinese Holstein cows

Autor:	Ke-Qiong Tang, Guohua Hua, Shu-Jing Li, Liguo Yang, Yang-Hua Xie, Wu-Cai Yang, Chunyan Zhang
Rok vydání:	2011
Předmět:	Genetics Exon General Veterinary Genotype Animal Science and Zoology Single-strand conformation polymorphism Single-nucleotide polymorphism Gene polymorphism Biology Gene DNA sequencing Gonadotropin-releasing hormone receptor
Zdroj:	Livestock Science. 136:164-168
ISSN:	1871-1413
Popis:	The present study attempts to explore a predictor to forecast superovulation response on the basis of associations between superovulation performance and gene polymorphism, variation in the bovine type I gonadotropin releasing hormone receptor (GnRHRI) gene was investigated using PCR-single-strand conformational (PCR-SSCP) and DNA sequencing. Two single nucleotide polymorphisms (SNPs) of G286A and T340C were found in exon I of the bovine GnRHRI gene and evaluated its associations with superovulatory response in 104 Chinese Holstein cows. In polymorphic locus 286, all cows without superovulation response were mutations with genotype of GG. Individuals with GA genotype had a significant increase in total number of ova (TNO) (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fd51acd0cf3748decf76dff104bcc547 https://doi.org/10.1016/j.livsci.2010.08.012 Zobrazit plný text záznamu Full Text from ScienceDirect