Comparison of prognosis of FIGO stage IB 1 adenocarcinoma and squamous cell carcinoma who were treated primarily by surgery

Autor: Ki Heon Lee, Jae Yun Lim, Seok Ju Seong, Jae Sik Hong, Myung Seop Song, Chong Taik Park, Kyung Taek Lim, Jae Uk Shim, Tae Jin Kim
Rok vydání: 2006
Předmět:
Zdroj: Korean Journal of Gynecologic Oncology. 17:213
ISSN: 1738-6543
DOI: 10.3802/kjgo.2006.17.3.213
Popis: Objective:The objective of this study was to compare clinical and pathologic variables and prognosis of FIGO stage IB 1 adenocarcinoma and squamous cell carcinoma of uterine cervix who were treated primarily by surgery. Methods:From May 1982 to October 2000, 2,209 patients with invasive cancer of the uterine cervix were diagnosed and treated at Cheil Hospital. A retrospective review was performed of 533 patients with stage IB1 squamous cell carcinoma (group A) and 84 with adenocarcinoma (group B) of cervix who treated primarily by type 3 hysterectomy and pelvic and paraaortic lymphadenectomy. Results:Age, endometrial extension, lymph node metastasis and postoperative adjuvant therapy were not different between two group. There were more the lymphovascular space invasion in group A (136 patients, 25.5%) than group B (9 patients, 10.7%) (p<0.0046). 5 year survival were 95.0% vs 93.8% for group A and group B (p=0.75). Using univariate analysis, pelvic node metastasis, paraaortic metastasis, postoperative adjuvant therapy were significant for survival. Multivariate analysis of 5 year survival revealed independent prognostic factor as postoperative adjuvant therapy. Conclusion:Prognosis of FIGO stage IB1 cervical cancer patients who were treated by primarily by type 3 hysterectomy and pelvic and paraaortic lymphadenectomy between adenocarcinoma and squamous cell carcinoma was found to be same.
Databáze: OpenAIRE