Influence of long-term oxygen therapy on cardiac acceleration and deceleration capacity in hypoxic patients with chronic obstructive pulmonary disease

Autor:	Z Reed, R E Davies, Keir Lewis, Joe Annandale, Lindsay D’Silva, Michael Lewis
Rok vydání:	2011
Předmět:	COPD medicine.medical_specialty Physiology business.industry medicine.medical_treatment General Medicine medicine.disease Heart rate turbulence Surgery Ageing Physiology (medical) Internal medicine Oxygen therapy Heart rate Cardiology Medicine Signal averaging Circadian rhythm Young adult business
Zdroj:	Clinical Physiology and Functional Imaging. 31:258-265
ISSN:	1475-0961
DOI:	10.1111/j.1475-097x.2011.01010.x
Popis:	Summary Background: There is increasing interest in cardiovascular co-morbidities of chronic obstructive pulmonary disease (COPD). Heart rate turbulence (HRT) and phase-rectified signal averaging (PRSA) techniques quantify the heart’s acceleration/deceleration capacities. We postulated that these methods can help assess the integrity of cardiac control in hypoxic COPD. Methods: Eight hypoxic stable COPD patients, nine healthy age-matched older adults and eight healthy young adults underwent ECG monitoring for 24 h. Patients with COPD were also monitored following 4 weeks of standardized oxygen therapy. HRT measures [turbulence onset (TO), turbulence slope (TS)] and PRSA-derived acceleration/deceleration (AC, DC) indices were quantified within 6-h blocks to assess circadian variation. Results: There were between-group differences for variables TS, DC and AC (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::fd492f4a8c5160927951e7f0b3734538 https://doi.org/10.1111/j.1475-097x.2011.01010.x Zobrazit plný text záznamu Plný text