A 21-Year-Old Woman with Hepatomegaly
| Autor: | Caroline R. Barry MD, Amr M. Zaki MD, Vicki Munro MD, Glenn Patriquin MD MSc, Weei-Yuarn Huang MD, Karthik Tennankore MD |
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| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Canadian Journal of General Internal Medicine. 10 |
| ISSN: | 2369-1778 1911-1606 |
| DOI: | 10.22374/cjgim.v10i3.46 |
| Popis: | We report the case of a 21-year old woman with uncontrolled diabetes mellitus type 1 presenting with tender hepatomegaly and mildy elevated liver enzymes, with negative investigations for common causes. She was diagnosed by liver biopsy with glycogenic hepatopathy, an uncommon and likely under-recognized complication of poor glycemic control. The disease is typically reversible after weeks to months of appropriate insulin therapy and is unlikely to lead to permanent liver disease. Our patient was treated with a new insulin regimen and analgesics and discharged home. Unfortunately, on follow-up imaging in our patient 10 months later, her hepatomegaly persists. Her glycemic control remains unchanged and she has since been admitted to hospital twice for episodes of diabetic ketoacidosis. |
| Databáze: | OpenAIRE |
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