ChemInform Abstract: Copper-Catalyzed Insertion into Heteroatom-Hydrogen Bonds with Trifluorodiazoalkanes
| Autor: | Stephen C. Hyde, Janis Veliks, Marc Taillefer, Benoit Liegault, Veronique Gouverneur, David Grassi |
|---|---|
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | ChemInform. 47 |
| ISSN: | 0931-7597 |
| DOI: | 10.1002/chin.201628060 |
| Popis: | Copper-catalyzed Si-H, B-H, P-H, S-H, and N-H insertion reactions of 2,2,2-trifluoro-1-diazoethane and 1-aryl 2,2,2-trifluorodiazoethanes generated a large number of new fluorine-containing chemical entities for medicinal chemists. With selected Si-H and B-H insertion reactions, we demonstrate successful extension to asymmetric catalysis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text