Retrospective Evaluation of CO2 Laser Conization in Pregnant Women with Carcinoma in situ or Microinvasive Carcinoma
| Autor: | Mitsuhiro Tsuritani, Taeko Kataoka, Haruhiko Ueda, Yasushi Kotani, Hiroshi Hoshiai, Yoh Watanabe |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Gynecology
medicine.medical_specialty Co2 laser business.industry Obstetrics Carcinoma in situ Obstetrics and Gynecology Cancer Retrospective cohort study medicine.disease Cervical intraepithelial neoplasia female genital diseases and pregnancy complications Microinvasive carcinoma Reproductive Medicine Cervical intraepithelial neoplasia 3 Carcinoma medicine business |
| Zdroj: | Gynecologic and Obstetric Investigation. 68:230-233 |
| ISSN: | 1423-002X 0378-7346 |
| DOI: | 10.1159/000236366 |
| Popis: | Background: We evaluated the safety and efficacy of CO2 laser conization in pregnant women with cervical intraepithelial neoplasia 3/carcinoma in situ (CIN3/CIS) or microinvasive carcinoma (MIC). Objectives: A total of 49 pregnant women with biopsy-proven CIN3/CIS (30 patients) or MIC (19 patients) were studied.Methods: Retrospective analysis based on clinical records. Results: Median age and median week of gestation were 31 years (range: 22–39) and 17 weeks (range: 7–33), respectively. The median length of cervix resected by conization, median duration of surgery and median blood loss were 14 mm (range: 5–23), 20 min (range: 7–35) and 78 ml (range: 10–797), respectively. One biopsy-proven CIN3/CIS patient was diagnosed with Federation of Gynecology and Obstetrics (FIGO) Ia2 and 3 biopsy-proven MIC patients were diagnosed with FIGO Ib1 based on conization specimens. A total of 35 patients could be followed until delivery, of which 27 (77.1%) patients delivered transvaginally. Although 8 patients (22.9%) had a cesarean section and 6 patients (17.1%) delivered preterm, no conization-related obstetric complications were observed. Conclusion: Since it results in few obstetric complications, CO2 laser conization within 20 mm of length can be considered a safe procedure for pregnant women. |
| Databáze: | OpenAIRE |
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