| Popis: |
Geometric changes in lipid membranes are essential in cellular processes like vesicle trafficking and fusion1. Hydrophobic insertion of amphipathic helices and membrane scaffolding by proteins are classical membrane bending mechanisms2.However, recent research suggests that crowding of peripherally bound proteins can drive membrane curvature independent of the protein's scaffold or membrane insertion3. Proteins with large hydrodynamic radii should contribute the most to membrane expansion, and thus to membrane bending. |
