Autor: |
Christopher S. Frampton, Paul L. Coe, W.Anthony Thomas, Ian W. A. Whitcombe, Peter Maunder, Joseph Armstrong Martin |
Rok vydání: |
2002 |
Předmět: |
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Zdroj: |
Journal of Fluorine Chemistry. 115:13-20 |
ISSN: |
0022-1139 |
Popis: |
The fluorination of (+)- chiro -inositol with SF 4 /HF under moderate conditions affords a single product studied by 1 H and 19 F and 13 C NMR spectroscopy. These have been fully assigned with the aid of other physical techniques and compared with a computer-generated model. This data indicate the product to be 2α,3β-difluoro-7-oxabicyclo[2.2.1]heptane-5α,6α-sulfite 3 which was subsequently confirmed by single-crystal X-ray analysis. A mechanism for the reaction is proposed and is compared with that proposed for the formation of the product obtained from the fluorination of myo -inositol. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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