| Autor: |
Leendert J. Bakker, Jan G. van den Tweel, Loek de Graaf, Roel A. de Weger, Jan Verhoef, Piet Joling, Bart A. van de Wiel |
| Rok vydání: |
1994 |
| Předmět: |
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| Zdroj: |
In Vivo Immunology ISBN: 9781461360629 |
| DOI: |
10.1007/978-1-4615-2492-2_27 |
| Popis: |
Infection of bone marrow cells by HIV-1 might be a principle cause for the bone marrow myelodysplasia and peripheral blood cytopenias in HIV-1 infected patients1. Infection of immature cells in bone marrow may have long-lasting effects on the haematopoiesis2. Although the CD4 molecule is considered as the major receptor of HIV-1, also other factors may be decisive for binding and modulation of the retrovirus3-5. In this study we present data of the binding and the infection of bone marrow cells by HIV-1. Furthermore the role of anti-HIV-1 antibody and complement on binding of HIV-1 is evaluated. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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