Autor: V. V. Pigarev, A. S. Solovyev, D. V. Krylsky, Kh. S. Shikhaliev
Rok vydání: 2002
Předmět:
Zdroj: Chemistry of Heterocyclic Compounds. 38:992-993
ISSN: 0009-3122
Popis: We have established that when acetone cyanohydrin is heated with thiosemicarbazide in aqueous medium, 3-mercapto-6,6-dimethyl-1,2,4-triazin-5-one and 2-methyl-2-thiosemicarbazidopropanoic acid are formed. Cyclization of the latter in dioxane in the presence of H3BO3 leads to 2-amino-5,5-dimethyl-1,3,4-thiadiazin-6-one.
Databáze: OpenAIRE