Merck’s Reaction Review Policy: An Exercise in Process Safety

Autor: Harold B. Wood, Nobuyoshi Yasuda, Rebecca T. Ruck, Ephraim M. Bassan, Thomas Vickery, Izzat T. Raheem, Dienemann Erik A, Khateeta M. Emerson, Guy R. Humphrey, David M. Tschaen
Rok vydání: 2013
Předmět:
Zdroj: Organic Process Research & Development. 17:1611-1616
ISSN: 1520-586X
1083-6160
DOI: 10.1021/op4002033
Popis: Process safety is an important consideration not only when conducting reactions on manufacturing scale, but also on lab and kilo lab scale. This contribution presents a discussion of Merck’s Reaction Review policy, originally specific to Process Chemistry and now applied broadly across the whole chemistry organization. Details of the policy and case studies are included.
Databáze: OpenAIRE