130INSULIN-LIKE GROWTH FACTOR-1 AND INTERLEUKIN-11 AS POSSIBLE SURVIVAL FACTORS FOR THE BOVINE PREIMPLANTATION EMBRYO EXPOSED TO STRESS
Autor: | F. D. Jousan, Peter J. Hansen, J. Hernández-Cerón, C. M. Franco |
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Rok vydání: | 2004 |
Předmět: |
medicine.medical_specialty
Theriogenology Embryo Embryo culture Reproductive technology Biology Cryopreservation Andrology chemistry.chemical_compound Endocrinology medicine.anatomical_structure Reproductive Medicine chemistry Gossypol Immunology Genetics medicine Animal Science and Zoology Blastocyst Molecular Biology Gametogenesis Developmental Biology Biotechnology |
Zdroj: | Reproduction, Fertility and Development. 16:188 |
ISSN: | 1031-3613 |
Popis: | Both IGF-1 and interleukin-11 (IL-11) are survival factors that modify response to cell injury. Moreover, IGF-1 promotes preimplantation development (Mol. Reprod. Dev. 62, 489) and IL-11 has been reported to reduce effects of heat shock on bovine embryos (Theriogenology 59, 343). For this study, it was hypothesized that IGF-1 and IL-11 improve survival of bovine embryos exposed to lethal stimuli. Embryos were produced in vitro and cultured in KSOM medium. Treatment effects were analyzed using least squares ANOVA with the GLM procedure of SAS (SAS Inst., Inc., Cary, NC, USA). In Exp. 1, 100ngmL−1 IGF-1 increased (P |
Databáze: | OpenAIRE |
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